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Analytical studies on two amino acid derivatives of anticonvulsant activity

Pirianowicz-Chaber, E.; Paruszewski, R.

Acta Poloniae Pharmaceutica 59(4): 239-241

2002

ISSN/ISBN: 0001-6837
PMID: 12403296
Document Number: 549131
Qualitative and quantitative methods of analysis of two new amino acid derivatives, potential anticonvulsants of low neurotoxicity: N-acetyl-gamma-aminobutyric acid benzylamide (1) and N-melhyl-gamma-aminobutyric acid benzylamide (2) were developed. Qualitative analysis includes characteristic colour reactions, chromatographic (TLC) investigations, IR and UV spectra interpretation and quantitative analysis involves spectrophotometric, chromatographic (HPLC). acidimetric and argentomeric methods.

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