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Qualitative and quantitative analysis of new amino acid derivatives of anticonvulsant activity

Pirianowicz-Chaber, E.; Paruszewski, R.

Acta Poloniae Pharmaceutica 58(3): 147-149

2001

ISSN/ISBN: 0001-6837
PMID: 11712729
Document Number: 534402
Qualitative and quantitative methods for analysis of three new amino-acidic anticonvulsants of low neurotoxicity: pyrazole-3,5-dicarboxylic acid benzylamine (1), pyrazine-2-carboxylic acid benzylamine (2) and (R, S) N-acetyl-2-pyrrolidone-5-carboxylic acid benzylamide (3) have been developed. Qualitative analysis included characteristic reactions, chromatographic (TLC) investigations, IR and UV spectra interpretation and quantitative analysis involved spectrophotometric, chromatographic (HPLC) and acidimetric methods.

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