Hydrolysis of lorazepam with hydrochloric acid. Qualitative and quantitative analysis of byproducts of hydrolysis
Verweij, A.M.; Verheijden-de Bruyne, M.M.
Archiv für Kriminologie 174(1-2): 35-39
1984
ISSN/ISBN: 0003-9225 PMID: 6487009 Document Number: 222026
Results of the identification of some additional products in the hydrochloric acid hydrolysis of lorazepam are reported, together with some quantitative results about the hydrolysis products under varying circumstances. It appeared that the amount of byproducts was reduced by applying hydrochloric acid of good quality and further on hydrolysis time had to be short.