Effects of fatty acid amides on phosphatidylcholine hydrolysis catalyzed by phospholipase A2 in micelles
Andreiuk, G.M.; Kisel', M.A.; Litvinko, N.M.
Ukrainskii Biokhimicheskii Zhurnal 69(1): 32-36
1997
ISSN/ISBN: 0201-8470 PMID: 9454375 Document Number: 470973
The effect of fatty acid amides on the hydrolysis of natural phosphatidylcholine and its semisynthetic analog, dioleoyl phosphatidylcholine, catalyzed by phospholipase A2 in mixed micelles with Triton X-100 has been studied. Palmitoylamide, oleoylamide, and stearoylamide were shown to be the inhibitors of enzymatic phospholipid hydrolysis.
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