Pyrrole analogues of chloramphenicol. I. Synthesis and antibacterial activity of DL-threo-1- (1-methyl-4-nitropyrrole-2-yl) -2-dichloroacetamidopropane-1,3-diol
Krajewska, D.; Dabrowska, M.; Jakoniuk, P.; Rózański, A.
Acta Poloniae Pharmaceutica 57(3): 213-221
2000
ISSN/ISBN: 0001-6837 PMID: 11143711 Document Number: 523286
The seven-stage synthesis of a pyrrole analogue of chloramphenicol [IX] was described. The compound exhibits a significant antibacterial activity, over the 12-50% range of the chloramphenicol activity.
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