Antibacterial activity of 3- (1-methyl-5-nitro-2-imidazolylmethylideneamino) -2-oxazolidinone

Frost, B.M.; Valiant, M.E.; Dulaney, E.L.

Journal of Applied Bacteriology 38(2): 177-184

1975


ISSN/ISBN: 0021-8847
PMID: 1126879
Document Number: 86150
This nitroimidazole is related chemically to dimetridazole and ipronidazole; it is also similar to furazolidone by substitution of 5-nitrofuran by 5-nitroimidazole. The compound was more effective than benzylpenicillin and nitrofurantoin in reducing the number of staphylococci in the kidneys of mice infected with Staphylococcus aureus..

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