The induction of stomach cancer in monkeys with N-methyl-N'-nitro-N-nitrosoguanidine
Sharashidze, L.K.; Beniashvili, D.S.; Sherenesheva, N.I.; Turkiia, N.G.
Voprosy Onkologii 35(3): 335-338
1989
ISSN/ISBN: 0507-3758 PMID: 2705317 Document Number: 340336
Gastric tumors were detected in 2 out of 9 apes following MNNG treatment with a total dose of 800-848 mg/kg (40 mg/kg, thrice a month, 49-50 weeks, via gastric probe). The characteristics, course, symptoms and histologic patterns of the tumors proved comparable with similar neoplasms in humans.
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