Choroid plexus carcinoma: report of 15 cases
Bleggi-Torres, L.F.; Urban, L.A.; Antoniuk, A.; Carboni, P.; Ramina, R.; Gugelmin, E.S.
Arquivos de Neuro-Psiquiatria 58(2b): 505-511
2000
ISSN/ISBN: 0004-282X PMID: 10920414 Document Number: 523285
Choroid plexus carcinoma (CPC) are rare central nervous system tumours derived from choroid plexus epithelium, affecting mainly children under 3 years of age. We present a clinical, epidemiological and histopathological study of 15 cases of CPC. Ten patients were male. Age ranged from 4 months to 21 years (mean=3,4). The lateral ventricles were affected in 73,3% of cases. Main symptom were: hydrocephalus (62.5%), intracranial hypertension (25%) and convulsion (12.5%). The patients were treated by surgery with partial resection in 75% of cases and total resection in 25%. There was one death due to surgical complication, 85.7% of patients had recurrence of tumours with mean survival rate of 13.6% months after diagnosis. Only one patient remain alive 5 years after initial treatment. These results support the poor prognosis and high mortality rate of CPC.