Synthesis and biological activity of some 4-substituted pyrimidines and fused pyrimidines

El-Bahaie, S.; el-Deeb, A.; Assy, M.C.

Die Pharmazie 46(1): 26-28

1991


ISSN/ISBN: 0031-7144
PMID: 1907010
Document Number: 387802
The synthesis of 4-beta-cyanoethylthiopyrimidine 2 and 4-chloropyrimidine 8a was chieved from 4-mercapto-5-acetylpyrimidine (1a). Also the synthesis of thienopyrimidine-7,7-dioxide 6, 4-arylaminopyrimidines 9a-e, 4-alkoxypyrimidines 11a, b, pyrimidoquinazoline 10, thienopyrimidines 19a, b and tetrazolopyrimidine 18 was described.

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