Nonpeptide angiotensin Ii receptor antagonists: synthesis and biological activity of 1H-imidazo and 1H-[1,2,3]-triazolo fused derivatives
Delgado, F.; Pastor, J.; García-Navío, J.L.; Vaquero, J.J.; Alvarez-Builla, J.; Sunkel, C.; de Casa-Juana, M.F.; Priego, J.G.; Santos, L.R.; Statkow, P.R.; Straumann, D.
Farmaco 52(3): 147-155
1997
ISSN/ISBN: 0014-827X PMID: 9212449 Document Number: 476806
A series of 1H-Imidazo and 1H-[1,2,3]-Triazolo fused derivatives have been obtained and tested as non peptide AII receptor antagonists. Modification of the classical biphenyl moiety to a 4-arylthienyl fragment afforded interesting activities.
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