Synthesis of imidazo [4,5-b] pyridine-7-carboxylic acid and some of its derivatives with expected antituberculous activity
Bukowski, L.
Polish Journal of Pharmacology and Pharmacy 32(5): 767-772
1980
ISSN/ISBN: 0301-0244 PMID: 6791143 Document Number: 166902
The title acid 2 and its methyl ester 3, hydrazide 4, hydrazone 5, amide 6, nitrile 7, amidoxime 8 and thioamide 9 have been obtained. As a result of methylation of 2 with diazomethane N-CH3 derivatives of these compounds 10-17 were obtained and their structure was preliminary established as 3-CH3 compounds. Some of the obtained compounds were investigated for their tuberculostatic activity.
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