Nitrogen bridgehead compounds. Part 7: Synthesis of anti-atherosclerotic pyrido[1,2-a]pyrimidines
Hermecz, I.; Mészáros, Z.; Vasvári-Debreczy, L.; Horváth, A.; Virág, S.; Sipos, J.
Arzneimittel-Forschung 29(12): 1833-1835
1979
ISSN/ISBN: 0004-4172 PMID: 546421 Document Number: 143181
The synthesis of 9-substituted-pyrido[1,2-a]pyrimidines are described. The new compounds exhibit antiatherosclerotic effects. The 3-ethoxycarbonyl-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-9-acetic acid (Chinoin-123) has the most favourable effects.
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