Synthesis of some 2- (3,4-dimethoxy-phenyl) -1,3-propanediamines as potential dopaminergic agents
Shafik, R.M.; Ibrahim, E.A.; el-Khawass, E.M.; el-Hawash, S.A.; el-Dardiry, S.A.
Die Pharmazie 44(2): 115-118
1989
ISSN/ISBN: 0031-7144 PMID: 2568640 Document Number: 338914
The bilateral diamino analogs namely N,N'-dialkyl-N,N'-diaralkyl- and N,N,N',N'-tetraalkyl-2-(3,4-dimethoxyphenyl)-1,3-propanediamine s were synthesized. The biochemical determination of the brain levels of dopamine and norepinephrine as well as of brain monoamine oxidase (MAO) activity was performed.
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