Search for potential anticonvulsant drugs: part I. Synthesis of 2-phenyl-3-benzimidazolyl/-alkyl (alkyl-aryl) --quinazolin (3H) -4-one
Misra, V.S.; Pandey, R.N.; Dhavan, K.N.
Polish Journal of Pharmacology and Pharmacy 29(5): 543-548
1977
ISSN/ISBN: 0301-0244 PMID: 593969 Document Number: 118644
By the condensation of 2-phenyl-3-carboxy alkyl/aryl-quinazolin (3H)-4-one and substituted (unsubstituted o-phenylenediamine, 15 new 2-phenyl-3-benzimidazolyl(-alkyl/alkyl-aryl) -quinazolin (3H)-4-ones were prepared. All 15 compounds were tested for anticonvulsant activity in mice against pentylenetetrazol . A good protection was obtained by most of the compounds.
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