Synthesis and antimicrobial activity of 1- (p-substituted) phenyl-3- (p-alkoxy) phenyl-4-phenyl-azetidin-2-ones

Diurno, M.V.; Cristinziano, A.; Mazzoni, O.; Piscopo, E.; Bolognese, A.

Farmaco 50(2): 143-148

1995


ISSN/ISBN: 0014-827X
PMID: 7766278
Document Number: 454859
A series of 1-(p-substituted)phenyl)-3-(p-alkoxy)phenyl-4-phenyl-azetidin-2-ones 1a-20a, was synthesized and characterized. Their antimicrobial activity, against Gram+ and Gram- bacteria and Fungi, was tested. The compounds 8a, 13a, 14a, 18a and 6a, 9a, 10a showed remarkable activity respectively against Pseudomonas aeruginosa and against Fungi.

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