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Synthesis and antimicrobial activity of some new isonicotinoylamino acid and dipeptide derivatives

el-Naggar, A.M.; Hussein, M.E.; el-Nemma, E.M.; Samour, A.A.

Il Farmaco; Edizione Scientifica 40(9): 662-670

1985

ISSN/ISBN: 0430-0920
PMID: 4076430
Document Number: 550
The synthesis of a series of isonicotinoylamino acids (II-XI) and some of their corresponding methyl esters (XII-XVIII), hydrazides (XXI-XXVI), dipeptide methyl esters (XXVII-XLII), the di- and tri-glycine peptides (XIX-XX) is described. Sixteen of various isonicotinoylamino acid and dipeptide derivatives were found to possess specific antimicrobial activities towards different microorganisms.

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Synthesis and antimicrobial activity of some new isonicotinoylamino acid and dipeptide derivatives

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