Synthesis and antimicrobial activity of new 5-aryl-2-hydroxy-3 (2H) -pyrrolinone derivatives
Kozminykh, V.O.; Igidov, N.M.; Kozminykh, E.N.; Semenova, Z.N.; Andreichikov YuS
Die Pharmazie 47(4): 261-263
1992
ISSN/ISBN: 0031-7144 PMID: 1518883 Document Number: 399420
The synthesis of some 1-substituted 5-aryl-2-hydroxy-2-methoxycarbonylmethyl-3(2H)-pyrrolinones is described. The results of microbiological screening are given. They indicate that 2-methylene-3(2H)-furanone and 2-hydroxy-3(2H)-pyrrolinone derivatives exhibit a rather low antimicrobiological activity.
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