Synthesis of new N-[4- (4-aryl- and 4-heteroaryl-1-piperazinyl) butyl]derivatives of 1-methyl-5-oxobicyclo[2.2.1]heptane-2,3-dicarboximide with an expected anxiolytic activity
Kossakowski, J.; Zawadowski, T.; Kuśmierczyk, J.
Acta Poloniae Pharmaceutica 55(4): 315-318
1998
ISSN/ISBN: 0001-6837 PMID: 9821397 Document Number: 486927
Preparation of a number of derivatives of 1-methyl-5-oxobicyclo[2.2.1]heptane-2,3-dicarboximide with a potential anxiolytic activity has been described. New analogs of Tandospirone i.e. derivatives of bicyclo[2.2.1]heptane (10), were aimed at.
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