Synthesis and antimicrobial activity of some new (sulfon-amidophenyl) -amide derivatives of N- (m-nitrobenzoyl) -D,L-methionine
Pintilie, O.; Sunel, V.; Profire, L.ţa.; Pui, A.
Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 111(3): 773-778
2007
ISSN/ISBN: 0048-7848 PMID: 18293716 Document Number: 614994
In order to obtain new compounds with potential antimicrobial activity some new (sulfon-amidophenyl)-amide derivatives of N-(m-nitrobenzoil)-D,L-methionine have been synthesized. The compounds have been obtained by decyclization reaction of 2-(m-nitrophenyl)-4-(beta-P-methylthioethyl)- delta2-5-oxazolinone with various sulfonamides. The chemical structure of the new sulfonamides was confirmed by elemental analysis data and IR and 1NMR spectral measurements. The compounds were also investigated for their antimicrobial activity using Staphylococcus aureus, Escherichia coli, Listeria monocytogenes and Proteus vulgaris strains.