Synthesis and antimicrobial activity of 2-arylmethylpyrrolidine derivatives

Aboul-Enein, M.N.; El-Difrawy, S.M.; Nofal, Z.M.; El-Azzouny, A.A.; El-Hawary, S.

Acta Pharmaceutica Suecica 19(4): 309-316

1982


ISSN/ISBN: 0001-6675
PMID: 7136738
Document Number: 192339
The synthesis and antimicrobial activity of certain 1-acetyl-2-(arylmethyl)-3-hydroxy-4-ethoxycarbonylpyrrolidines 3 a.sbd.e and 1-acetyl-2-(arylmethyl)-3-hydroxy-4-hydroxymethylpyrrolidines 3 f.sbd.j are described. Some of the compounds exhibited notable activity against certain bacteria and Candida albicans, especially compounds 3 d and 3 h.

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