Synthesis, chemical and pharmacological properties of some N-aminoalkyl derivatives of 3,4-pyridinedicarboxamides
Sĺadowska, H.; Potoczek; Sieklucka-Dziuba, M.; Semczuk, A.; Kleinrok, Z.
Farmaco 50(11): 761-768
1995
ISSN/ISBN: 0014-827X PMID: 8593173 Document Number: 449032
The synthesis and properties of some N-aminoalkyl derivatives of 3,4-pyridinedicarboximides (1-15) are reported. Imide 11, containing 2-hydroxy-3-(4-phenyl-1-piperazinyl) propyl substituent at the nitrogen atom, proved to have the lowest toxicity and, at very high dosages, to be the most pharmacologically active.
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