Possible antifertility agents, part III. Synthesis of 4- (substituted aminomethyl) -5, 6, 7-trimethoxy phthalid methiodides and 1-N-aminoacetyl-benz [1, 6] diazocin-5-ones
Kulkarni, Y.D.; Abdi, S.H.; Sharma, V.L.; Mukherjee, S.
Biological Memoirs 13(2): 141-144
1987
ISSN/ISBN: 0379-8097 PMID: 12282446 Document Number: 364777
12 new heterocyclic compounds containing methoxy groups and/or amine side chain residues have been synthesized and 1 had some activity in an antiimplantation assay. The compounds included 7 4-(substituted aminomethyl)5,6,7-trimethoxy phthalid methiodides and 5 1-N-aminoacetylbenz[1,6]diazocin-5-ones. 50% anti-implantational activity was observed on a morpholino compound, 4-(4-morpholinomethyl)-5,6,7-trimethoxy phthalid methiodide.