Synthesis of 3-aryl-2-substituted-4 (3H) -quinazolines as potential antimicrobial agents
Farghaly, A.M.; Mohsen, A.; Omar, M.E.; Khalil, M.A.; Gaber, M.A.
Farmaco 45(4): 431-438
1990
ISSN/ISBN: 0014-827X PMID: 2119178 Document Number: 351995
Three new series of 4(3H)-quinazolinone derivatives were synthesized, namely: [3-Aryl-4(3H)-quinazolinon-2-yl]-methylenehydrazino-(N- substituted)-thiocarbamides, 3-Aryl-2-(3-substituted-4-phenyl-2,3-dihydrothiazol-2-ylidenehy drazonomethyl)-4 (3H)-quinazolinones and 3-Aryl-2-(3-substituted-4-oxothiazolidin-2-ylidenehydrazonometh yl)-4(3H)-quinazolinones. The antimicrobial activities of the synthesized compounds were also studied.
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