Analysis of the cell cycle duration of cells of permanent line L-929

Petrov, I.P.; Neguliaev, I.A.; Tsupkina, N.V.

Tsitologiia 54(3): 214-217

2012


ISSN/ISBN: 0041-3771
PMID: 22645985
Document Number: 658896
The direct measurement of the cell cycle duration in L-929 cells was performed using time-lapse photography. The cell cycle duration was 15.77 +/- 0.08 h with a standard deviation of 1.54 +/- 0.06 h. The experimental value fit to a normal distribution with a correlation coefficient 0.999. High homogeneity of this parameter and a wide range of variability of the karyotype (58-66 chromosomes) indicate that there is no correlation between these characteristics of L-929 cells. It is also shown that the difference between cell cycle durations of daughter cells tent to zero and fits by an exponent.

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