Top Abstract Purchase Related
Home
>
Node
>
Subnode

Negative pion irradiation of mammalian cells. II. A comparative analysis of cell-cycle progression after exposure to pi-mesons and cobalt gamma-rays

Schlag, H.; Weibezahn, K.F.; Lücke-Huhle, C.

International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine 33(1): 1-10

1978

ISSN/ISBN: 0020-7616
PMID: 304847
Document Number: 126495
The effect of negative pi-mesons on cell-cycle progression of exponentially-growing V 79 monolayer cultures was examined by flow-microfluorometric analysis. Comparison with proliferative changes of the same cell-line after cobalt gamma-irradiation yielded r.b.e. values (relative biological effectiveness) of 2.2 for both, G2+M accumulation and division delay after irradiation at the pion peak. A dose-dependent prolongation of S-phase was found after Co gamma-irradiation which, however, was not detectable after pi-exposure. This observation is so far the only qualitative difference demonstrated in the effects of the two types of radiation.

Document emailed within 1 workday
Secure & encrypted payments

Sheĭkina, T.A.; Belostotskaia, G.B.; Arkhipov, M.V. 1978: DNA replication in Hela cells after gamma irradiation. I. the period of DNA replicative synthesis after the irradiation of cells in the G1 phase with gamma rays in large doses Tsitologiia 20(8): 962-966
Synzynys, B.I.; Brozmanová, J.; Sklobovskaia, M.V.; Saenko, A.S. 1985: DNA replication in mammalian cells after exposure to factors of a physical, chemical or biological nature. III. 5-Fluorodeoxyuridine induces DNA synthesis in cells not suppressed by gamma irradiation Tsitologiia 27(2): 236-240
Collyn-d'Hooghe, M.; Hemon, D.; Gilet, R.; Curtis, S.B.; Valleron, A.J.; Malaise, E.P. 1981: Comparative effects of 60Co gamma-rays and neon and helium ions on cycle duration and division probability of EMT 6 cells. A time-lapse cinematography study International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine 39(3): 297-306
Vexler, F.B.; Kublik, L.N.; Eidus, L.Kh.; Vexler, A.M. 1982: Kinetics of repair of DNA single-strand breaks in cultured mammalian cells. Part I. The dependence on irradiation dose and cell cycle stage International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine 41(4): 453-457
Hecquet, C.; Nafziger, J.; Ronot, X.; Marie, J.P.; Adolphe, M. 1985: Flow cytometric analysis of pentakis(aziridino)thiatriazadiphosphorine oxide (SOAz)-induced changes in cell cycle progression of Hela and HL-60 cells Cancer Research 45(2): 552-554
Dobrowolski, S.F.; Stacey, D.W.; Harter, M.L.; Stine, J.T.; Hiebert, S.W. 1994: An E2F dominant negative mutant blocks E1A induced cell cycle progression Oncogene 9(9): 2605-2612
Goodhead, D.T.; Thacker, J. 1977: Inactivation and mutation of cultured mammalian cells by aluminium characteristic ultrasoft X-rays. I. Properties of aluminium X-rays and preliminary experiments with Chinese hamster cells International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine 31(6): 541-559
Harm, H. 1978: Damage and repair in mammalian cells after exposure to non-ionizing radiations. I. Ultraviolet and visible light irradiation of cells of the rat kangaroo (Potorous tridactylus) and determination of photorepairable damage in vitro Mutation Research 50(3): 353-366
Brüsselbach, S.; Möhle-Steinlein, U.; Wang, Z.Q.; Schreiber, M.; Lucibello, F.C.; Müller, R.; Wagner, E.F. 1995: Cell proliferation and cell cycle progression are not impaired in fibroblasts and ES cells lacking c-Fos Oncogene 10(1): 79-86
Yasuda, H. 1992: Regulation of cell cycle by cdc2 kinase in mammalian cells Seikagaku. Journal of Japanese Biochemical Society 64(1): 1-13
Malone, J.F.; Porter, D.; Hendry, J.H. 1974: The r.b.e. of 60Co gamma rays with respect to 300 kVp x-rays for the survival of HeLa S-3 and CHO cells, irradiated in different states of proliferation International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine 26(4): 355-362
Ehm, I.; Magdon, E.; Regel, K. 1975: V. Comparative impulse cytophotometric investigations for redistribution of lymphoma cells in vivo after treatment with 60Co-gamma-rays and fast neutrons Archiv für Geschwulstforschung 45(8): 753-766
Deĭneko, I.V.; Kel', A.E.; Kel'-Margulis, O.V.; Wingender, E.; Ratner, V.A. 2003: Modeling dynamics of gene net, regulating the cell cycle in mammalian cells Genetika 39(9): 1285-1292
Armelin, H.A.; Armelin, M.C. 1979: Cell cycle regulation in mammalian cells: hormones and commitment to DNA synthesis Archivos de Biologia y Medicina Experimentales 12(3): 319-324
Barker, T.D.; Weissman, D.; Daucher, J.A.; Roche, K.M.; Fauci, A.S. 1996: Identification of multiple and distinct CD8+ T cell suppressor activities: dichotomy between infected and uninfected individuals, evolution with progression of disease, and sensitivity to gamma irradiation Journal of Immunology 156(11): 4476-4483
Kirillova, T.V.; Seregina, T.B.; Bil'din, V.N. 1992: The regulation of DNA repair processes in mammalian cells. III. The effect of epidermal growth factor on the postradiation recovery of the cell cycle in human A 431 cells and embryonic fibroblasts Tsitologiia 34(5): 94-104
Charcosset, J.Y.; Bendirdjian, J.P.; Lantieri, M.F.; Jacquemin-Sablon, A. 1985: Effects of 9-OH-ellipticine on cell survival, macromolecular syntheses, and cell cycle progression in sensitive and resistant Chinese hamster lung cells Cancer Research 45(9): 4229-4236
Stürzbecher, H.W.; Maimets, T.; Chumakov, P.; Brain, R.; Addison, C.; Simanis, V.; Rudge, K.; Philp, R.; Grimaldi, M.; Court, W. 1990: P53 interacts with p34cdc2 in mammalian cells: implications for cell cycle control and oncogenesis Oncogene 5(6): 795
Nakamura, T.; Takauji, R.; Kamiya, K.; Kawai, Y.; Iwasaki, H.; Tohyama, K.; Yamauchi, T.; Ueda, T. 1997: Intracellular pharmacodynamics of ara-C and flowcytometric analysis of cell cycle progression in leukemia chemotherapy Leukemia 11(Suppl 3): 548-551
Shu, J.; Hitomi, M.; Stacey, D. 1996: Activation of JNK/SAPK pathway is not directly inhibitory for cell cycle progression in NIH3T3 cells Oncogene 13(11): 2421-2430