Top Abstract Purchase Related
Home
>
Node
>
Subnode

A complex interferon inducer potentiates the functional macrophage activity during Staphylococcal infection

Karpov, A.V.; Yakovenko, L.F.

European Journal of Medical Research 11(7): 285-289

2006

ISSN/ISBN: 0949-2321
PMID: 16899422
Document Number: 602575
The antibacterial effect of a new type I interferon inducer, an yeast RNA-tilorone molecular complex (MC), was studied using a model of staphylococcal infection. The MC taken in experimental doses being optimal interferon-inducing ones accelerates the Staphylococcus aureus elimination from mice organisms accompanied by increased functional ability (phagocytosis and bactericide activity) of peritoneal macrophages. The conclusion is that the MC antibacterial activity detected is mediated by its interferon-inducing properties.

Document emailed within 1 workday
Secure & encrypted payments

Vasilenko, R.N.; Denisov, L.A.; Galaktionov, V.G. 1989: Effect of recombinant human alpha-interferon (reaferon) on macrophage functional activity in mice Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 7: 100-104
Il'in, G.I.; Aksenov, O.A.; Fomina, T.I. 1978: Effect of nonantigenic interferon inducer on the reactivity of the lymphoid-macrophage system and anti-influenza resistance of the body Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 2: 12-16
Lazarenko, L.N.; Spivak, N.I.; Umanskiĭ, V.I.; Vikhot', N.E.; Ivanenko, V.K. 1992: Effects of alpha-interferon on the level of adenosine metabolism enzymes and bactericidal activity of macrophages in staphylococcal infection Biulleten' Eksperimental'noi Biologii i Meditsiny 114(7): 63-66
Umenai, T.; Saito, N.; Yashima, T. 1978: Fungal infection and immunity.--Protective effect of interferon inducer on Candida albicans infection in mice Rinsho Byori. Japanese Journal of Clinical Pathology 26(4): 345-348
Gribencha, S.V.; Nosik, N.N.; Ershov, F.I.; Barinskiĭ, I.F. 1983: Therapeutic activity of the combined use of an interferon inducer and vaccine in experimental rabies Voprosy Virusologii 28(5): 590-594
Purcell, R.H.; London, W.T.; McAuliffe, V.J.; Palmer, A.E.; Kaplan, P.M.; Gerin, J.L.; Wagner, J.; Popper, H.; Lvovsky, E.; Wong, D.C.; Levy, H.B. 1976: Modification of chronic hepatitis-B virus infection in chimpanzees by administration of an interferon inducer Lancet 2(7989): 757-761
Bel'skiĭ, V.V.; Zakarian, L.M.; Prokopenko, L.G.; Chalyĭ, G.A. 1988: Effect of terrilytin on the activity of nonspecific resistance factors during immunization with staphylococcal anatoxin and staphylococcal infection Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 5: 90-95
Sukhikh, G.T.; Meerson, F.Z.; Van'ko, L.V.; Poverennyĭ, A.M.; Fuks, B.B. 1984: Effect of interferon and its liposome-incorporated inducer on the recovery of natural killer activity after immobilization stress Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 1984(11): 81-84
Onishi, T.; Machida, T. 1994: A study on direct antitumor activity of bropirimine (oral interferon inducer) for renal cell carcinoma Hinyokika Kiyo. Acta Urologica Japonica 40(3): 195-200
Lvovsky, E.A.; D'Souza, J.; Eng, D.; D'Souza, D.; Lvovsky, B.; Hetland, R.; Craver, W.L.; Sobel, S.H. 1988: Tumor response to interferon inducer and radiation effect of serum interferon levels Journal of Biological Regulators and Homeostatic Agents 2(1): 1-6
Hamburg, S.I.; Cassell, G.H.; Rabinovitch, M. 1980: Relationship between enhanced macrophage phagocytic activity and the induction of interferon by Newcastle disease virus in mice Journal of Immunology 124(3): 1360-1364
Barsukov, A.A.; Zemskov, V.M.; Beznosenko, S.A. 1986: Analysis of macrophage functional activity during adhesion Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 1: 3-8
Chekanovskaia, L.A. 1997: Gamma-plant as a new nontoxic interferon inducer Voprosy Virusologii 42(3): 123-126
Doskocil, J.; Fuchsberger, N.; Vetrák, J.; Lackovic, V.; Borecký, L. 1971: Double-stranded f 2 phage RNA as interferon inducer Acta Virologica 15(6): 523
Edwards, C.K.; Hedegaard, H.B.; Zlotnik, A.; Gangadharam, P.R.; Johnston, R.B.; Pabst, M.J. 1986: Chronic infection due to Mycobacterium intracellulare in mice: association with macrophage release of prostaglandin E2 and reversal by injection of indomethacin, muramyl dipeptide, or interferon-gamma Journal of Immunology 136(5): 1820-1827
Kountouras, J.; Boura, P.; Tsapas, G. 1998: In vivo effect of granulocyte-macrophage colony-stimulating factor and interferon combination on monocyte-macrophage and T-lymphocyte functions in chronic hepatitis B leukocytopenic patients Hepato-Gastroenterology 45(24): 2295-2302
Liamina, S.V.; Vedenikin, T.I.; Borodovitsyna, O.A.; Kruglov, S.V.; Malyshev, I.I. 2012: M1 and M2 macrophage phenotypes functional activity as essential components in innate immune response assessment Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 98(8): 1030-1035
Sopotsinskaia, E.B.; Umanskiĭ, V.I.; Lisniak, I.A. 1988: Effect of a limitation of the food ration on macrophage functional activity and angiogenesis in mice with metastasizing tumors Voprosy Pitaniia 6: 48-50
Poliakova, A.M.; Lomazova, K.D.; Kravchenko, A.V.; Maleev, V.V. 1989: The action of interferon and reaferon on the functional activity of human thrombocytes Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 11: 52-54
Sysoeva, G.M.; Razvorotnev, V.A.; Fadina, V.A.; Kostomakha, A.N. 1989: Study of immunoregulating properties of an interferon inducer in animals with various reactions to the antigen Antibiotiki i Khimioterapiia 34(4): 276-279