Effect of recombinant human alpha-interferon (reaferon) on macrophage functional activity in mice
Vasilenko, R.N.; Denisov, L.A.; Galaktionov, V.G.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 7: 100-104
1989
ISSN/ISBN: 0372-9311 PMID: 2683517 Document Number: 342377
The influence of human recombinant alpha 2-interferon (reaferon) on the parameters of the phagocytic activity of mouse peritoneal macrophages (migration, spreading, adhesion and absorption of corpuscular antigen) has been studied. Reaferon in doses of 5-5 X 10(2) I. U./ml has been found to produce a stimulating effect on all parameters under study. The data obtained in this study suggest that a stimulating effect on the functional activity of macrophages is the same for recombinant (alpha 2) interferon and natural alpha-interferon.