Mechanisms of pyrimidine derivatives systemic immunomodulating effect
Slabnov, I.D.; Cherepnev, G.V.; Tsibulkin, A.P.; Garaev, R.S.
Eksperimental'naia i Klinicheskaia Farmakologiia 60(3): 65-67
1997
ISSN/ISBN: 0869-2092 PMID: 9324405 Document Number: 474906
Experiments on guinea pigs showed that xymedone in a dose of 30 mg/kg stimulates nucleic acid synthesis in thymocytes and increases the blood serum nucleic acid content. Xymedone increased secretion of endogenous DNA by human lymphocytes stimulated with PNA in vitro. The systemic immunotropic mechanisms of pyrimidine derivatives are discussed.
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