Development of resistance to DDT in Musca domestica L. from sublethal doses of sodium arsenate
Drobozina, V.P.
Meditsinskaia Parazitologiia i Parazitarnye Bolezni 40(6): 695-701
1971
ISSN/ISBN: 0025-8326 PMID: 5147629 Document Number: 37891
The possibility was investigated of resistance being developed to organochlorine and organophosphorus insecticides (DDT, fenitrothion and trichlorphon (chlorophos)) by flies (Musca domestica L.) when given sublethal doses of the stomach poison sodium arsenate. It was found that the administration of sodium arsenate in sublethal doses in the food of adults of two insecticide-susceptible strains of house-flies over 11 and 30 successive generations did not change their sensitivity either to sodium arsenate or to organophosphorus insecticides, but resulted in 200-fold increase in resistance to DDT in both strains.The level of resistance developed was variable in the first few generations and a small proportion of flies remained susceptible even when a high level of resistance had developed. This resistance to DDT was not associated with increased intensity of dehydrochlorination of DDT and DDE. Resistance developed to an insecticide unaccompanied by a concomitant development of resistance to another insecticide that had been administered cannot be designated as 'cross' or 'multiple' and the term 'side resistance' is proposed for this type.