New derivatives of 5-nitroimidazole: synthesis and antiparasitic activity
Alcalde, E.; Maños, L.; Dinares, I.; Valls, N.; Elguero, J.; Escario, J.A.; Martinez, A.R.; Igea, A.; Osuna, A.; Ruiz-Perez, L.M.
Farmaco 44(11): 1095-1107
1989
ISSN/ISBN: 0014-827X PMID: 2701965 Document Number: 326728
The synthesis and the antiparasitic evaluation of twelve new 5-nitroimidaole derivatives has been carried out. The most effective compounds were the less hydrophilic pyridinium and imidazolium salts (IV), (V) and (X), and above all the tetrahydropyridine derivatives (XII) and (XIII).
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