3,5-Diamino-1,2,6-thiadiazine 1,1-dioxide derivatives: synthesis and antiparasitic activity
Arán, V.J.; Bielsa, A.G.; Goya, P.; Ochoa, C.; Páez, J.A.; Stud, M.; Contreras, M.; Escario, J.A.; Jiménez, M.I.; Durán, E.A.
Il Farmaco; Edizione Scientifica 41(11): 862-872
1986
ISSN/ISBN: 0430-0920 PMID: 3803564 Document Number: 277156
The synthesis of new 3,5-diamino-1,2,6-thiadiazine 1,1-dioxide derivatives is described and their structures discussed on the basis of 1H and 13C-N.M.R. data. The antiparasitic activity of these and related compounds was evaluated. The bacterial mutagenicity of the parent compound (I) was studied.
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