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Search for anti-inflammatory preparations among the derivatives of succinic acid heteryl amides

Kabachnyĭ, V.I.; Chernykh, V.P.; Drogovoz, S.M.; Golubenko, I.A.; Bogutskaia, E.E.

Farmakologiia i Toksikologiia 50(1): 94-97

1987

ISSN/ISBN: 0014-8318
PMID: 3556563
Document Number: 302561
The antiinflammatory activity and acute toxicity of 44 derivatives of heteryl amides of succinic acid (acids, esters, amides) were studied. This series of compounds was found to be promising for the search of nonsteroidal, practically nontoxic antiphlogistics. The structural-pharmacological analysis was performed and the dependence of the biological effect on the compound structure was revealed.

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Dolzhenko, A.V.; Kolotova, N.V.; Kozminykh, V.O.; Syropyatov, B.Y.; Kotegov, V.P.; Godina, A.T. 2002: Hypoglycemic effect of several substituted amides and acylhydrazides of succinic acid Die Pharmazie 57(11): 776-778
Shvarts, G.I.; Siubaev, R.D. 1988: The search for and study of new nonsteroidal anti-inflammatory preparations Farmakologiia i Toksikologiia 51(2): 15-21
Wilimowski, M.; Witkowska, M.; Barczyńska, J.; Kedzierska, L.; Wojewodzki, W.; Felsztyńska, J. 1979: Central action of new imido derivatives of succinic acid Archivum Immunologiae et Therapiae Experimentalis 27(3): 389-396
Lange, J.; Rump, S.; Ilczuk, I.; Lapszewicz, J.; Rabsztyn, T.; Walczyna, K. 1977: Synthesis and properties of cyclic derivatives of succinic acid with anticonvulsant activity Die Pharmazie 32(10): 579-581
Filatova, G.F.; Kuznetsova, G.A.; Bobkov, I.G. 1986: Catecholamine levels in rats during cooling and administration of succinic acid derivatives Biulleten' Eksperimental'noi Biologii i Meditsiny 102(9): 315-316
Volchegorskiĭ, I.A.; Rassokhina, L.M.; Miroshnichenko, I.I. 2013: Cerebroprotective effect of 3-oxypyridine and succinic acid derivatives in experimental diabetes mellitus Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 113(6): 50-61
Volchegorskiĭ, I.A.; Miroshnichenko, I.I.; Rassokhina, L.M.; Faĭzullin, R.M.; Malkin, M.P.; Priakhina, K.E.; Kalugina, A.V. 2014: Anxiolytic and antidepressant effects of 3-oxypiridine and succinic acid derivatives in the acute phase of alloxan-induced diabetes in rats Eksperimental'naia i Klinicheskaia Farmakologiia 77(4): 14-20
Kowalczyk-Bronisz, S.H.; Zabska, R. 1986: Studies on the derivatives of aziridine. I. synthesis and immunopharmacological analysis of amides of alpha-aziridinyl- beta-/p-chlorobenzoyl/-propionic acid Archivum Immunologiae et Therapiae Experimentalis 34(3): 333-350
Bahekar, S.S.; Shinde, D.B. 2003: Synthesis and anti-inflammatory activity of some [2-amino-6-(4-substituted aryl)-4-(4-substituted phenyl)-1,6-dihydropyrimidine-5-yl]-acetic acid derivatives Acta Pharmaceutica 53(3): 223-229
Kabachnyĭ, V.I.; Filippova, L.I.; Drogovoz, S.M.; Chernykh, V.P.; Savchenko, L.G. 1984: Search for cholagogic preparations in a series of heterylamide derivatives of ethylene (ethane) dicarboxylic acids Farmakologiia i Toksikologiia 47(4): 91-94
Tiurenkov, I.N.; Bagmetova, V.V.; Ivanova, O.V.; Berestovitskaia, V.M.; Vasil'eva, O.S.; Ostrogliadov, E.S. 2011: Anxiosedative properties of heteryl(aryl)-containing hexahydrobenzofuranon derivatives Eksperimental'naia i Klinicheskaia Farmakologiia 74(1): 15-18
Lanza, F.L. 1999: A safe non-steroidal anti-inflammatory drug--the search continues Italian Journal of Gastroenterology and Hepatology 31(5): 386-387
Tian, S.L.; Zhao, S.W.; Zhu, A.T.; Fang, Y.; Li, K.Q. 1993: Studies on anti-tumor agents. I: Synthesis and anti-cancer activity of amino acid derivatives of norcantharidin Yao Xue Xue Bao 28(11): 870-875
Bukin, I.V.; Plikhtiak, I.L.; Draudin-Krylenko, V.A.; Iartseva, I.V.; Orlova, L.M. 1987: Ascorbigen and its derivatives--depot preparations of ascorbic acid Bioorganicheskaia Khimiia 13(4): 539-545
Yamamoto, H.; Saito, C.; Inaba, S.; Awata, H.; Yamamoto, M. 1973: Novel quinazoline derivatives. II. a new anti-inflammatory agent, SL-512 Arzneimittel-Forschung 23(9): 1266-1271
Shaĭdrov, V.V.; Ionov, I.D. 1988: Evaluation of the immunotoxicity of sulfanilamide, anti-inflammatory and antihistaminic preparations Farmakologiia i Toksikologiia 51(3): 82-84
Pilli, G.; Erdoğan, H.; Sunal, R. 1993: Some new benzoxazolinone derivatives with analgesic and anti-inflammatory activities Arzneimittel-Forschung 43(12): 1351-1354
Shapiro, A.A.; Meksin, V.A.; Abilev, S.K.; Akin'shina, L.P.; Fonshteĭn, L.M. 1978: Mutagenic activity of antitubercular preparations: isonicotinic acid hydrazide and its derivatives Tsitologiia i Genetika 12(4): 343-348
Mosti, L.; Sansebastiano, L.; Fossa, P.; Schenone, P.; Mattioli, F. 1992: 1-Phenyl-1H-indazole derivatives with analgesic and anti-inflammatory activities Farmaco 47(3): 357-365
Lagorce, J.F.; Lakhdar, M.; Fatimi, J.; Nefaoui, S.; Raby, C. 1992: Synthesis and anti-inflammatory activity of 2-pyridyl-2-thiobenzothiazole derivatives Farmaco 47(12): 1477-1485