Synthesis and analgesic antiinflammatory activities of 2-aryl-ethenyl-4-aryl-thiazole-5-acetic acids

Bonina, F.; Guerrera, F.; Sarvà, M.C.; Siracusa, M.A.; Caruso, A.; Leone, M.G.; Amico Roxas, M.

Il Farmaco; Edizione Scientifica 42(12): 905-913

1987


ISSN/ISBN: 0430-0920
PMID: 3502406
Document Number: 292099
A series of fifty-five 2-aryl-ethenyl-4-aryl-thiazole-5-acetic acids (IV-LVIII) were synthesized and evaluated for analgesic and antiinflammatory activities. Most of the synthesized compounds showed a good analgesic activity whereas some exhibited significant antiinflammatory activity.

Document emailed within 1 workday
Secure & encrypted payments