Incorporation of ubiquinones into lipid vesicles and inhibition of lipid peroxidation
Landi, L.; Cabrini, L.; Tadolini, B.; Sechi, A.M.; Pasquali, P.
Italian Journal of Biochemistry 34(5): 356-363
1985
ISSN/ISBN: 0021-2938 PMID: 4077468 Document Number: 257878
Ubiquinone incorporation into vesicles to evaluate its antioxidative effect on lipid peroxidation has been studied. Only sonication and not vortication allows comparable incorporation patterns of the various ubiquinone homologues into lipid vesicles. The measure of malondialdehyde, a convenient index for determining the extent of autoxidation, shows that both the naturally occurring homologues and synthetic shorter-chain ones, also in the oxidized form, possess similar antioxidant efficiency.