Top Abstract Purchase Related
Home
>
Node
>
Subnode

3,3'-bi-1,3-thiazolidine]-4,4'-dione system. I. Synthesis, conformational analysis and pharmacological activities of 2,2'-diaryl derivatives

Vigorita, M.G.; Previtera, T.; Basile, M.; Fenech, G.; Costa De Pasquale, R.; Occhiuto, F.; Circosta, C.

Il Farmaco; Edizione Scientifica 39(12): 1008-1023

1984

ISSN/ISBN: 0430-0920
PMID: 6335693
Document Number: 240286
The 2 configurational isomers, dl and meso of some 2,2'-diaryl-. The antiinflammatory effect, which in some compounds was higher than that of indomethacin and phenylbutazone, appeared to be a function of the relative disposition of the substituents at position 2 and 2', generally the meso isomers were more active than the dl ones. The lipophilicity of the tested compounds was determined by reversed-phase TLC.

Document emailed within 1 workday
Secure & encrypted payments

Mohsen, A.; Omar, M.E.; Salama, H.M.; Eshba, N.H. 1985: Novel thiazolidine-2,4-dione-4-thiosemicarbazone and 4-[(3,4-diaryl-3H-thiazol-2-yl)azo]thiazolidin-2-one derivatives: synthesis and evaluation for antimicrobial and anticancer properties Il Farmaco; Edizione Scientifica 40(1): 49-57
Basile, M.; Previtera, T.; Vigorita, M.G.; Fenech, G.; Pizzimenti, F.C. 1986: 3,3'-bi-1,3-thiazolidine]-4,4'-dione system. III. Evaluation of the antimicrobial and antitumor properties of 2,2'-disubstituted derivatives and their 1,1'-disulfones Il Farmaco; Edizione Scientifica 41(8): 637-643
Zhao, L.Q.; Yang, Z.; Zhang, S.F. 2001: 5,6-diaryl-2,3-dihydro-1-pyrrolizinone derivatives synthesis and antiiflammatory and analgesic activities Yao Xue Xue Bao 36(4): 258-261
Obniska, J.; Pawłowski, M.; Kołaczkowski, M.; Czopek, A.; Duszyńska, B.; Klodzińska, A.; Tatarczyńska, E.; Chojnacka-Wójcik, E. 2003: Synthesis and 5-HT1A/5-HT2A receptor activity of new N-[3-(4-phenylpiperazin-1-yl)-propyl] derivatives of 3-spiro-cyclohexanepyrrolidine-2,5-dione and 3-spiro-beta-tetralonepyrrolidine-2,5-dione Polish Journal of Pharmacology 55(4): 553-557
Banci, F.; Bulgini, M.J.; Tubaro, E. 1971: Synthesis and some pharmacological activities of 4-alkylamino-2,3-dimethyl-l-phenyl-3-pyrazolin-5-one derivatives Arzneimittel-Forschung 21(11): 1665-1667
Vladzimirskaia, E.V.; Kirchenko, B.M. 1975: Synthesis and properties of bicyclic derivatives of thiazolidine Farmatsevtychnyi Zhurnal 1: 41-43
Vladzimirskaia, E.V.; Kirchenko, B.M. 1975: Synthesis and properties of bicyclic derivatives of thiazolidine Farmatsevtychnyi Zhurnal 1: 41-43
de Lima, J.G.; Perrissin, M.; Chantegrel, J.; Luu-Duc, C.; Rousseau, A.; Narcisse, G. 1994: Synthesis and pharmacological evaluation of some 3-phenacyl-5-benzylidene-thiazolidine-2,4-diones Arzneimittel-Forschung 44(7): 831-834
Vladzimirs'ka, O.V.; Hnidets', V.I.; Stebliuk, P.M. 1979: Synthesis of bicyclic derivatives of thiazolidine containing a benzoyloxy group in their molecules Farmatsevtychnyi Zhurnal 3: 71-72
Rusjakovski, B.; Kobe, J.; Brdar, B.; Japelj, M.; Valcavi, U. 1982: Synthesis and antiviral activities of 2-substituted azino-3-(D-arabinofuranosyl)-5-carboxymethylene-thiazolidine-4-ones Il Farmaco; Edizione Scientifica 37(11): 764-780
Kamiński, K.; Obniska, J. 2008: Synthesis and anticonvulsant properties of new 1-(2-pyridinyl)- 3-substituted pyrrolidine-2,5-dione derivatives Acta Poloniae Pharmaceutica 65(4): 457-465
Malinka, W.; Sieklucka-Dziuba, M.; Rajtar-Cynke, G.; Gasior, M.; Kleinrok, Z. 1995: Synthesis and pharmacological study of some derivatives of pyrazolo[4,3-c]pyrido[3,2-c]-1,2-thiazine-5,5-dioxide, a novel heterocyclic ring system Farmaco 50(1): 29-35
Nacci, V.; Filacchioni, G.; Porretta, G.C. 1972: Research on compounds with psychotropic activity. I. Synthesis of 5-phenylpyrrolo-(2,1-d)(1,5)-benzothiazepin-6,6-dioxide and 1,2,3,3a,4,5-hexahydro-5-phenylpyrrolo-(2,1-d)(1,5)-benzothiazepin-1,4-dione-6,6-dioxide, derivatives of a new heterocyclic system Il Farmaco; Edizione Scientifica 27(11): 1003-1017
Zawadowski, T.; Skowron, A.A.; Suski, S.; Rump, S.; Jakowicz, I. 1995: Synthesis and pharmacological profile of bicyclo[2.2.2]octane derivatives: N-(1-aryl-4-piperazinyl-butyl) derivatives of 7-isopropyl-6-methyl- and 1-isopropyl-4-methylbicyclo[2.2.2]oct-5-ene-2,3-dicarboxyimide Acta Poloniae Pharmaceutica 52(2): 129-132
Toniolo, C.; Valle, G.; Crisma, M.; Bonora, G.M.; Lelj, F.; Cristinziano, P.L.; Barone, V.; Nisato, D. 1990: Theoretical and experimental conformational analysis of two diastereomeric "Val"-statine derivatives Peptide Research 3(1): 27-34
Joshi, K.C.; Pathak, V.N.; Jain, S.K. 1980: Studies of potential organo-fluorine antibacterial agents. Part 5: Synthesis and antibacterial activity of some new fluorine-containing indole-2,3-dione derivatives Die Pharmazie 35(11): 677-679
Nawojski, A.; Liszkiewicz, H.; Nawrocka, W.; Ernest, K.; Szymańska-Kosmala, M. 1983: Synthesis and pharmacological investigations of derivatives 6-azabenzodiazepines Polish Journal of Pharmacology and Pharmacy 35(1): 77-85
Pedrazzoli, A.; Dall'asta, L.; Guzzon, V.; Ferrero, E. 1970: Synthesis and pharmacological activity of some adamantane derivatives Il Farmaco; Edizione Scientifica 25(11): 822-829
Longobardi, M.; Schenone, P.; Bargagna, A.; Matera, C.; Rossi, F.; Marmo, E. 1985: Synthesis and pharmacological activity of derivatives of exo-trimethylenenorbornane. V Il Farmaco; Edizione Scientifica 40(3): 162-169
Mirek, J.; Adamczyk, M.; Chojnacka-Wójcik, E.; Naparzewska, A. 1978: Synthesis and pharmacological screening of some N-carboxymethylbarbituric acid derivatives. i Polish Journal of Pharmacology and Pharmacy 30(5): 685-693