Top Abstract Purchase Related
Home
>
Node
>
Subnode

Pharmacological characteristics of a new phenyl analog of piracetam--4-phenylpiracetam

Bobkov, I.G.; Morozov, I.S.; Glozman, O.M.; Nerobkova, L.N.; Zhmurenko, L.A.

Biulleten' Eksperimental'noi Biologii i Meditsiny 95(4): 50-53

1983

ISSN/ISBN: 0365-9615
PMID: 6403074
Document Number: 213673
The central neurotropic effects of 4-phenylpyracetam, a new phenyl analog of pyracetam, were studied and compared with the effects of pyracetam, morpholene and 4-phenylpyrrolidone. 4-Phenylpyracetam was found to activate the operant behavior more powerfully, to remove psychodepressant effects of diazepam, to inhibit post-rotational nystagmus, and to prevent the development of retrograde amnesia. Unlike pyracetam, 4-phenylpyracetam exhibits a specific anticonvulsant action. When given in high doses, the compound under study produces psychodepressant effects.

Document emailed within 1 workday
Secure & encrypted payments

Pahwa, G.S.; Anand, K.K.; Johri, S.; Gupta, S.; Atal, C.K. 1987: Pharmacological and toxicological investigations of 7-hydroxy-4-phenyl-3(4-hydroxy-phenyl)-coumarin (OV1) Indian Journal of Experimental Biology 25(7): 450-453
Diurno, M.V.; Cristinziano, A.; Mazzoni, O.; Piscopo, E.; Bolognese, A. 1995: Synthesis and antimicrobial activity of 1-(p-substituted)phenyl-3-(p-alkoxy)phenyl-4-phenyl-azetidin-2-ones Farmaco 50(2): 143-148
Marakos, P.; Foscolos, G.B.; Fytas, G.; Kolocouris, N.; Vamvakidès, A. 1991: Synthesis and pharmacological study of alpha-phenyl-1-adamantanemethanamine Annales Pharmaceutiques Francaises 49(4): 214-221
Duro, F.; Condorelli, P.; Arrigo Reina, R. 1972: Synthesis and pharmacological activity of alkylamido-derivatives of 4-phenyl-3-isocoumarin acid Bollettino Chimico Farmaceutico 111(12): 740-748
Banci, F.; Bulgini, M.J.; Tubaro, E. 1971: Synthesis and some pharmacological activities of 4-alkylamino-2,3-dimethyl-l-phenyl-3-pyrazolin-5-one derivatives Arzneimittel-Forschung 21(11): 1665-1667
Mirek, J.; Chojnacka-Wójcik, E.; Tatarzyńska, E.; Wiczyńska, B. 1985: Synthesis of 3-phenyl-3-phenylthiopropionic acids, amides, amines and studies on their pharmacological properties Il Farmaco; Edizione Scientifica 40(9): 701-708
Zawadzka, J.; Bogdal, M. 1984: Thiazole derivatives. V. Synthesis and pharmacological screening of amides of 4-phenyl-5-thiazolecarboxylic acids Acta Poloniae Pharmaceutica 41(6): 633-640
Makliakov, I.S.; Karkishchenko, N.N.; Bardakhch'ian, E.A.; Kharlanova, N.G. 1992: The ultrastructural characteristics of the changes in sections of the rat brain under piracetam exposure Eksperimental'naia i Klinicheskaia Farmakologiia 55(6): 9-12
Fanelli, O. 1973: Pharmacological and toxicological study of a new psychotropic stimulant: the 2-phenyl-5-dimethyl-tetrahydro-1,4-oxazine, in comparison with d,l-amphetamine, phenmetrazine and pemoline-Mg Arzneimittel-Forschung 23(6): 810-816
Bonacchi, G.; Agostini, O.; Fedi, M.; Bacciarelli, C.; Boni, P.; Castellucci, A.; Perretti, F.; Manzini, S. 1988: Resolution and pharmacological properties of the enantiomers of the potent alpha-adrenoceptor antagonist 1-[2-ethoxy-2-(3'-pyridyl)ethyl]-4-(2'-methoxy-phenyl)piperazine Arzneimittel-Forschung 38(5): 650-654
Hullot, P.; Poudrel, J.M.; Muller, A.; Escale, R.; Rossi, J.C.; Girard, J.P.; Bonne, C. 1997: Synthesis and biochemical/pharmacological profile of the novel leukotriene B4 receptor antagonist sodium (1S*, 3S*)-1-hydroxy-3-[(3 R*S*,E)-3-hydroxy-7-phenyl-1-hepten-1-yl]-1-cyclohexane acetate Arzneimittel-Forschung 47(1): 51-58
Brach, E.J.; Montour, M.; St Amour, G. 1973: Cancellation of spectrophotometer system characteristics using an analog computer Laboratory Practice 22(10): 631-632
Ziegelhoeffer A.; De Jong J.W.; Ferrari R.; Turi Nagy L. 1989: Anti-fertility agents 45. Synthesis and activity of 1,2-cis-1-(p-(β-pyrrolidinoethoxy)phenyl)-2-phenyl-5-methoxyindane European Journal of Medicinal Chemistry 24(2): 193-197
Dhar, J.D.; Setty, B.S.; Duran, S.; Kapil, R.S. 1991: Biological profile of 2-[4-(2-N-piperidinoethoxy) phenyl]-3-phenyl (2H) benzo (b) pyran--a potent antiimplantation agent in rat Contraception 44(4): 461-472
Coudert, P.; Rubat, C.; Couquelet, J.; Tronche, P. 1990: Synthesis of 6-[(4-imidazol-1-yl)-phenyl]-4-phenyl 4,5-dihydro-2H-pyridazin-3-one: a potential blood platelet aggregation inhibitor Journal de Pharmacie de Belgique 45(3): 191-195
Sel'kova, E.P.; Semenenko, T.A.; Nosik, N.N.; Iudina, T.I.; Amarian, M.P.; Lavrukhina, L.A.; Pantiukhova, T.N.; Tarasova, G.I. 2001: Effect of amyxin--a domestic analog of tilorone--on characteristics of interferon and immune status of man Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 4: 31-35
Sarles, H.; Camatte, R. 1970: Therapeutic action of phenyl-dimethoxy-2'-4' phenyl-methyl-carbinol and of a vesicular endothelium extract in dyspeptic disorders, fat intolerance and steatorrhea Marseille Medical 107(6): 513-516
Simkhovich, B.Z.; Meĭrena, D.V.; Khagi, K.B.; Kalvin'sh, I.I.; Lukevits, E.I. 1987: Biochemical characteristics of the anti-ischemic action of the new structural analog of gamma-butyrobetaine 3-(2,2,2,-trimethylhydrazine)propionate Farmakologiia i Toksikologiia 50(2): 100-104
Bruno, O.; Ranise, A.; Bondavalli, F.; Schenone, P.; D'Amico, M.; Filippelli, A.; Filippelli, W.; Rossi, F. 1993: 3,5-diphenyl-1H-pyrazole derivatives. XI. N-aryl-5(3)-phenyl-4-(3,5- diphenyl-1-pyrazolyl)-3(5)-pyrazole amines, 5-substituted 4,5-dihydro-3-phenyl-4-(3,5-diphenyl-1-pyrazolyl)-1H-pyrazoles and 2,6-disubstituted 1,6-dihydro-4- phenyl-5-(3,5-diphenyl-1-pyrazolyl)pyrimidines with antipyretic, antiinflammatory and other activities Farmaco 48(7): 949-966
Islam, M.; Siddiqui, A.A. 2010: Synthesis, antituberculostatic, antifungal and antibacterial activities of 3-substituted phenyl-6-substituted phenyl-1,2,4-triazolo[4,3-b]pyridazines Acta Poloniae Pharmaceutica 67(5): 555-562