Synthesis of oligonucleotides containing the hypermodified base, alpha-putrescinylthymine

Takeda, T.; Ikeda, K.

Nucleic Acids Symposium Series 12: 75-78

1983


ISSN/ISBN: 0261-3166
PMID: 6664879
Document Number: 212367
Self-complementary decadeoxyribonucleotides containing alpha-putrescinyl-thymidine (Put Thd), AAGAATTPCTT, AAGAATTCTPT, AAGAATTPCTPT, (p is the abbreviation of alpha-putrescinyl residue) were prepared by the phosphotriester method. Nuclease activities and Tm for their oligomers were investigated by comparison of AAGAATTCTT.

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