Effect of trimethylglycine on lipid metabolism in experimental atherosclerosis in rabbits
Panteleĭmonova, T.N.; Zapadniuk, V.I.
Farmakologiia i Toksikologiia 46(4): 83-85
1983
ISSN/ISBN: 0014-8318 PMID: 6617841 Document Number: 197622
It has been shown in adult rabbits aged 8 months with experimental cholesterol atherosclerosis that administration of trimethylglycinee in a dose of 0.5 g/kg reduces the elevated content of total and ester-bound cholesterol, beta-lipoproteins, total lipids in the blood serum and that of total cholesterol and triglycerides in the liver. Little toxicity and high efficacy of trimethylglycin in experimental atherosclerosis make this compound prospective in the light of its use as an antisclerotic agent.