Effect of adiachrome on the lipid metabolism in experimental diabetes mellitus
Maloshtan, L.N.; Sadek, O.; Khilia, V.P.; Kovalev, V.N.
Eksperimental'naia i Klinicheskaia Farmakologiia 67(1): 25-27
2004
ISSN/ISBN: 0869-2092 PMID: 15079904 Document Number: 568511
The effect of a new original hypoglycemic peroral drug adiachrome on the lipid metabolism was studied in experimental animals with alloxan induced diabetes. The drug action was evaluated in terms of the levels of ketone bodies, lipoprotein complexes, cholesterol, and malonic dialdehyde in the blood serum. Administered in a dose of 15 mg/kg, adiachrome decreased the level of ketone bodies, lipoproteins, cholesterol, and malonic dialdehyde in the blood serum in dynamics of the model pathology studied.