Effect of central m- and n-cholinergic agents on ovarian compensatory hypertrophy in rats
Anisimov, V.N.
Problemy Endokrinologii 24(5): 85-87
1978
ISSN/ISBN: 0375-9660 PMID: 704564 Document Number: 125043
Stimulation of the n-cholinergic structures by nicotine or depression of m-cholinergic structures by metamizyl inhibited the compensatory ovarian hypertrophy (COH) induced by hemiovariectomy in rats. Stimulation of m-cholinergic structure by arecoline or depression of n-cholinergic structures by n-cholinolytic IEM-506 eliminated the suppression of COH induced by diethylstilbestrol-propionate. The mediatory role of the central-m-cholinergic systems in the mechanisms of COH and that of n-cholinergic systems in the estrogen-induced suppression of COH is suggested.