Microdissection study of nephron growth during compensatory renal hypertrophy and postnatal ontogeny in rats
Goncharevskaia, O.A.; Ruziev, T.R.
Arkhiv Anatomii Gistologii i Embriologii 80(3): 89-92
1981
ISSN/ISBN: 0004-1947 PMID: 7259559 Document Number: 177973
Unilateral nephrectomy stimulates renal growth with preservation of linear dependence between its mass and that of the body as it is observed in normally growing rats. Increase in the renal mass by 50% at compensatory hypertrophy is depended on a proportional growth of nephrons and their segments. In young rats during the period of the most intensive development (1--2 month of age) the renal weight increases by 100% and the length of nephron -- by 30%. The data obtained demonstrate that renal hypertrophy develops, mainly, at the expense of growth of the nephrons and their segments.