Synthesis and biological activities of some 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives
Ikizler, A.A.; Demirbas, A.; Johansson, C.B.; Celik, C.; Serdar, M.; Yuksek, H.
Acta Poloniae Pharmaceutica 55(2): 117-123
1998
ISSN/ISBN: 0001-6837 PMID: 9673151 Document Number: 494779
Nine new 1,3,4-trisubstituted-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized and characterized by elemental analysis, 1H NMR, IR and UV spectra. These new and 30 recently reported 3,4-disubstituted- and 1,3,4-trisubstituted-4,5-dihydro-1H-1,3,4-triazol-5-ones were screened for antibacterial, antitumor and anti-HIV activities.
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