Synthesis and antiviral activities of 9-cyclopentylpurine derivatives

Kojima, E.; Ohta, K.; Miyawaki, S.; Date, T.; Machida, M.; Murakami, K.

Nucleic Acids Symposium Series 34: 107-108

1995


ISSN/ISBN: 0261-3166
PMID: 8841575
Document Number: 444772
The synthesis and anti-RSV (Rouse Sarcoma Virus) activity of HMCA, (+/-)-9-(2-hydroxymethyl-cyclopenthyl)-adenine, and its derivatives are described. It has been demonstrated that trans-HMCA has greater anti-RSV activity in tissue culture than cis-HMCA.

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