High fat diet, lipid peroxidation, and pancreatic carcinogenesis
Zhang, J.; Go, V.L.
Advances in Experimental Medicine and Biology 399: 165-172
1996
ISSN/ISBN: 0065-2598 PMID: 8937556 Document Number: 457123
Pancreatic cancer is the fifth leading cause of death from cancer in the USA. Animal studies examining the promotion of pancreatic cancer by a high-fat diet are reviewed. The mechanisms involved in carcinogenesis induced by bis(2-oxopropyl)amine are discussed. The antitumour effects observed with dietary fish oil and the protective effect of antioxidants in pancreatic cancer are considered.
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