Effect of liposomes on lipid peroxidation in the heart and liver in crush syndrome
El'skiĭ, V.N.; Stefanov, A.V.; Mareeva, T.E.; Kolesnikova, S.V.; Skobeleva, E.I.; Kas'ianova, E.V.
Ukrainskii Biokhimicheskii Zhurnal 65(5): 109-112
1993
ISSN/ISBN: 0201-8470 PMID: 8160290 Document Number: 419351
The increased lipid peroxidation has been determined to be one of general mechanisms of disturbance in the functional state of the heart and liver fraction cells, regularities of inter-system disturbance in metabolic activity under the crush syndrome have been revealed. Administration of lecithin liposomes results in the decreased POL levels, increased antioxidant capacity of the organism. That permits recommending to include liposomes into complex therapeutics of the crush syndrome as detoxicating, antiinflammatory and antihypoxic drug.