Effect of the lipid composition of liposomes on their clearance from the circulation and accumulation in the liver of mice

Burkhanov, S.A.; Torchilin, V.P.

Biulleten' Eksperimental'noi Biologii i Meditsiny 103(3): 299-301

1987


ISSN/ISBN: 0365-9615
PMID: 3828508
Document Number: 287199
The effect of phospholipid and ganglioside liposome composition on the liposome clearance from the circulation and accumulation in the mouse liver has been studied. It has been shown that liposomes constituting of liver lipids are quicker removed from the circulation and accumulated in the liver. Liver gangliosides increased liposome uptake by the mouse liver and their clearance from the circulation.

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