The effect of rotating magnetic fields on the growth of Deal's guinea pig sarcoma transplanted subcutaneously in guinea pigs
Schwartz, E.; Svejnochová, M.; Siposová, E.; Honzátková, Z.
Bratislavske Lekarske Listy 94(4): 213-217
1993
ISSN/ISBN: 0006-9248 PMID: 8353767 Document Number: 408229
The effect of rotating magnetic field (RMF) was studied on the growth of Deals' guinea pig sarcoma (DGPS) transplanted subcutaneously into the inguen of guinea pigs. The 0.2 ml of transplanted suspension contained 1.5-2.0 x 10(6) of vital DGPS cells. Over a period of 24 days the animals were daily two times exposed to RMF for 3 hours. The animals were sacrificed in chloroform anesthesia, the inguinal tumors, lungs and hearts were removed and weighed. The following findings were recorded: 1. RMF inhibited the growth of DGPS cells in experimental guinea pigs compared to control animals (p < 0.001); 2. In the experimental animals DGPS cells did not metastasize into the lung parenchyma; 3. The pathological characteristics of the tumors in the experimental and control group of guinea pigs tended to be different. (Tab. 3, Ref. 14.)