Growth and dissemination of adiaspores of Emmonsia crescens in experimentally infected guinea pigs and mice
Hamácek, F.; Kyntera, F.; Dvorák, J.; Otcenásek, M.; Adamcová, V.
Folia Parasitologica 18(1): 41-49
1971
ISSN/ISBN: 0015-5683 PMID: 5170751 Document Number: 33985
Following intraperitoneal inoculation, conversion of aleuriospores into adiaspores occurred within 7-14 days, apparently directly inside the peritoneal cavity. Penetration of the liver, spleen and kidney and (in guinea pigs only) of the mesenterial nodes occurred mainly by implantation. Lymphogenic or haematogenic spread to the brain, lungs and sexual organs occurred occasionally. The adiaspores formed in vivo were larger than those formed by E. crescens in vitro [RMVM 7, 2584]. White mice were about x 4700 more susceptible to intraperitoneally inoculated E. crescens than were guinea pigs.Systemic dissemination also occurred following intramuscular and, to a lesser extent, subcutaneous inoculation, indicating that adiaspiromycosis may occur following infection of wounds.