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Quantitative bacteriologic studies on experimentally infected laboratory animals. 3. Dynamics of germ counts in mice experimentally infected with Listeria monocytogenes

Selbitz, H.J.; Steinbach, G.; Meyer, H.

Archiv für Experimentelle Veterinarmedizin 40(4): 575-586

1986

ISSN/ISBN: 0003-9055
PMID: 3094474
Document Number: 283939
The bacteria were first detected in the liver and spleen 10 min after i/p inoculation of a large dose. Defence mechanisms at first brought about a fall in the number of bacteria. When a virulent strain was used, the bacteria began to multiply after 3-4 days. Infections in which the total number of bacteria in liver or spleen exceeded 108 were fatal. In immune mice, or when an attenuated strain was used, the numbers seldom reached this level. [Parts I and II were concerned with Salmonella-see VB 56, abst. 1416].

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