The role of HLA-DQ antigens in the induction of cytotoxic T lymphocytes
Porubská, S.; Buc, M.; Bencová, M.; Sausová, E.
Folia Biologica 39(5): 256-261
1993
ISSN/ISBN: 0015-5500 PMID: 8206171 Document Number: 408228
Investigating three pairs of HLA-DR (DRB1) identical unrelated persons on the induction of cytotoxic T lymphocytes (CTL) it was found that HLA-DQ antigens provided slight proliferative stimulus which was, however, sufficient for the generation of CTL. The results indicate that the HLA-DQ antigens do play a similar role in clinical bone marrow transplantation as the HLA-DR specificities.
Document emailed within 1 workday
Related Documents
Yang, H.; Li, J.; Zhao, Y. 2000: The role of MHC molecules on OSCC cells in the induction of autologous cytotoxic T lymphocytes Zhonghua Kou Qiang Yi Xue Za Zhi 35(4): 280-282Fan, J.; Bonavida, B. 1981: Studies on the induction and expression of T cell-mediated immunity. XII. The concomitant loss and recovery of membrane-associated Lyt-2 antigens, lymphocyte-target cell binding, and the antigen-specific and -nonspecific cytotoxic activity of alloimmune T lymphocytes after treatment with trypsin Journal of Immunology 127(5): 1856-1864
Lotzová, E. 1993: Recent approaches to induction of cytotoxic lymphocytes against leukemia Leukemia 7(Suppl): S69-S74
Kotomina, I.F.; Pletneva, T.P. 1977: Influence of soluble H-2 antigens on the cytotoxic effect and adsorption of immune lymphocytes Biulleten' Eksperimental'noi Biologii i Meditsiny 84(9): 333-336
Frost, P.; Rose, N.R. 1978: In vitro induction of lymphoblasts and cytotoxic lymphocytes with prostate tumor cells National Cancer Institute Monograph 1978(49): 169-172
Zeuthen, J.; Dzhandzhugazyan, K.; Hansen, M.R.; Kirkin, A.F. 1998: The immunogenic properties of human melanomas and melanoma-associated antigens recognized by cytotoxic T lymphocytes Bratislavske Lekarske Listy 99(8-9): 426-434
Hirakawa, Y. 1985: Immunological studies on herpetic keratitis. Induction of cytotoxic T lymphocytes in mouse splenocytes Nippon Ganka Gakkai Zasshi 89(1): 208-213
Seliger, B.; Harders, C.; Wollscheid, U.; Staege, M.S.; Reske-Kunz, A.B.; Huber, C. 1996: Suppression of MHC class I antigens in oncogenic transformants: association with decreased recognition by cytotoxic T lymphocytes Experimental Hematology 24(11): 1275-1279
Kall, M.A.; Hellström, I. 1975: Specific stimulatory and cytotoxic effects of lymphocytes sensitized in vitro to either alloantigens or tumor antigens Journal of Immunology 114(3): 1083-1088
Macphail, S.; Stutman, O. 1987: L3T4+ cytotoxic T lymphocytes specific for class i H-2 antigens are activated in primary mixed lymphocyte reactions Journal of Immunology 139(12): 4007-4015
Lawman, M.J.; Naylor, P.T.; Huang, L.; Courtney, R.J.; Rouse, B.T. 1981: Cell-mediated immunity to herpes simplex virus: induction of cytotoxic T lymphocyte responses by viral antigens incorporated into liposomes Journal of Immunology 126(1): 304-308
Peiper, M.; Goedegebuure, P.S.; Eberlein, T.J.; Zornig, C. 1997: Cytotoxic T-lymphocytes and the recognition of tumor antigens--an approach to "preventive tumor vaccination?" Zentralblatt für Chirurgie 122(3): 141-148
Piguet, P.F.; Vassalli, P. 1981: Collaboration between histoincompatible T and B lymphocytes: preferential induction in vivo of antibodies to antigens borne by foreign T cells Journal of Immunology 127(4): 1304-1307
Maezawa, N.; Yano, A. 1988: Requirement of Ia-positive nylon wool adherent cells for activation of cytotoxic T-lymphocytes specific to melanocyte-associated antigens in patients with Vogt-Koyanage-Harada's disease Japanese Journal of Ophthalmology 32(3): 348-357
Hoo, W.S.; Kranz, D.M. 1993: Role of CD8 in staphylococcal enterotoxin B-mediated lysis by cytotoxic T lymphocytes Journal of Immunology 150(10): 4331-4337
Tremblay, N.; Fontaine, P.; Perreault, C. 1994: T lymphocyte responses to multiple minor histocompatibility antigens generate both self-major histocompatibility complex-restricted and cross-reactive cytotoxic T lymphocytes Transplantation 58(1): 59-67
Gajdosová, E.; Oravec, C.; Mayer, V. 1981: Cell-mediated immunity in flavivirus infections. I. Induction of cytotoxic T lymphocytes in mice by an attenuated virus from the tick-borne encephalitis complex and its group-reactive character Acta Virologica 25(1): 10-18
Miller, R.G.; Derry, H. 1979: A cell population in nu/nu spleen can prevent generation of cytotoxic lymphocytes by normal spleen cells against self antigens of the nu/nu spleen Journal of Immunology 122(4): 1502-1509
Nagler-Anderson, C.; Verret, C.R.; Firmenich, A.A.; Berne, M.; Eisen, H.N. 1988: Resistance of primary CD8+ cytotoxic T lymphocytes to lysis by cytotoxic granules from cloned T cell lines Journal of Immunology 141(10): 3299-3305
Logunova, N.N.; Chernyshova, I.N.; Sidorova, E.V. 1995: The role of various subpopulations of murine B-lymphocytes in immune response to T-independent antigens Biulleten' Eksperimental'noi Biologii i Meditsiny 119(4): 402-405